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Seroprevalence of Celiac Disease in Tribal Population of High Altitude Area in Northern India
Brij Sharma1, Neetu Sharma2, Vishal Bodh1, Ashish Chauhan1, Rajesh Sharma1, Alka Singh4, Sidhant Sharma, Amit Sachdeva3 
1Department of Gastroentrology, 2Department of Physiology, 3Department of Community Medicine, IGMC, Shimla, India. 4Department of Gastroenterology & Human Nutrition Unit, AIIMS, New Delhi, India. 

Corresponding Author
Dr. Amit Sachdeva


Background: While celiac disease (CeD) is known to occur in many regions on the plains, there is a lack of data on its prevalence in high altitude area of India.
Methods: We screened serum samples of 332 participants in Lahaul and Spiti district of (mean altitude >4000 meter) Himachal Pradesh, for the estimation of prevalence of CeD in high altitude area. The screening of CeD was done using commercially available IgA human anti-tissue transglutaminase antibody (anti-tTG Ab) ELISA kit.
Results:  Of 332 samples (mean age 31.5±15.9 years) screened, two were found to have a positive anti-tTG Ab at low titre, suggesting a seroprevalence of 0.6%. 
Conclusions: The seroprevalence of CeD in high altitude area is 0.6%, almost equal to the rest of the country. The physicians working in high altitude areas need to be aware about CeD in their communities.